2021-10-31 | 49ers | Bears | 3 | 7:28 | 3 | 19 | SFO 16 | 9-16 | Jimmy Garoppolo pass complete short left to Deebo Samuel for no gain, touchdown Replay Assistant challenged the runner broke the plane ruling, and the original play was overturned. Jimmy Garoppolo pass complete short left to Deebo Samuel for 83 yards (tackle by DeAndre Houston-Carson) | 83 | | | |
2021-09-12 | 49ers | Lions | 3 | 8:08 | 3 | 8 | SFO 21 | 37-10 | Jimmy Garoppolo pass complete to Deebo Samuel for 79 yards, touchdown | 79 | | | |
2022-01-02 | 49ers | Texans | 3 | 13:34 | 3 | 6 | SFO 24 | 3-7 | Trey Lance pass complete short middle to Brandon Aiyuk for 43 yards (tackle by Eric Murray) | 43 | | | |
2021-09-26 | 49ers | Packers | 4 | 2:24 | 3 | 10 | SFO 25 | 21-27 | Jimmy Garoppolo pass complete short middle to George Kittle for 39 yards (tackle by Jaire Alexander) | 39 | | | |
2021-11-28 | 49ers | Vikings | 1 | 7:42 | 3 | 13 | SFO 22 | 0-7 | Jimmy Garoppolo pass complete deep left to Brandon Aiyuk for 37 yards (tackle by Patrick Peterson) | 37 | | | |
2022-01-09 | 49ers | Rams | 5 | 7:30 | 3 | 6 | SFO 42 | 24-24 | Jimmy Garoppolo pass complete short right to Jauan Jennings for 34 yards (tackle by Travin Howard and Darious Williams) | 34 | | | |
2022-01-02 | 49ers | Texans | 4 | 3:58 | 3 | 12 | SFO 28 | 17-7 | Trey Lance pass complete deep middle to George Kittle for 29 yards (tackle by Eric Murray). Penalty on Justin Reid: Defensive Pass Interference, 15 yards (declined) | 29 | | | |
2021-11-28 | 49ers | Vikings | 2 | 0:35 | 3 | 11 | MIN 30 | 7-14 | Jimmy Garoppolo pass complete short middle to Brandon Aiyuk for 24 yards (tackle by Harrison Smith and Xavier Woods) | 24 | | | |
2021-11-28 | 49ers | Vikings | 1 | 13:34 | 3 | 6 | SFO 33 | 0-0 | Jimmy Garoppolo pass complete deep middle to Jauan Jennings for 21 yards (tackle by Bashaud Breeland and Harrison Smith) | 21 | | | |
2021-10-31 | 49ers | Bears | 1 | 14:45 | 3 | 10 | SFO 33 | 0-0 | Jimmy Garoppolo pass complete short middle to Mohamed Sanu for 21 yards (tackle by Kindle Vildor) | 21 | | | |
2021-11-15 | 49ers | Rams | 2 | 8:23 | 3 | 7 | SFO 36 | 14-7 | Jimmy Garoppolo pass complete short middle to Deebo Samuel for 20 yards (tackle by Nick Scott) | 20 | | | |
2021-12-12 | 49ers | Bengals | 4 | 0:20 | 3 | 10 | CIN 48 | 20-20 | Jimmy Garoppolo pass complete deep left to George Kittle for 19 yards (tackle by Vonn Bell) | 19 | | | |
2021-10-31 | 49ers | Bears | 1 | 10:35 | 3 | 24 | CHI 49 | 0-0 | Jimmy Garoppolo pass complete deep middle to Mohamed Sanu for 19 yards (tackle by Alec Ogletree) | 19 | | | |
2021-11-15 | 49ers | Rams | 3 | 9:33 | 3 | 6 | SFO 41 | 21-7 | Jimmy Garoppolo pass complete short middle to Deebo Samuel for 19 yards (tackle by David Long and Nick Scott) | 19 | | | |
2021-11-15 | 49ers | Rams | 1 | 10:28 | 3 | 6 | SFO 22 | 0-0 | Jimmy Garoppolo pass complete short right to George Kittle for 18 yards (tackle by Jordan Fuller) | 18 | | | |
2021-10-10 | 49ers | Cardinals | 3 | 12:55 | 3 | 9 | SFO 37 | 0-10 | Trey Lance pass complete short left to Kyle Juszczyk for 18 yards (tackle by Jalen Thompson) | 18 | | | |
2021-10-24 | 49ers | Colts | 3 | 6:18 | 3 | 10 | SFO 20 | 12-13 | Jimmy Garoppolo pass complete short middle to Mohamed Sanu for 16 yards (tackle by Khari Willis and Kenny Moore) | 16 | | | |
2021-09-26 | 49ers | Packers | 3 | 8:40 | 3 | 9 | GNB 24 | 7-17 | Jimmy Garoppolo pass complete short right to Deebo Samuel for 16 yards (tackle by Adrian Amos) | 16 | | | |
2021-12-12 | 49ers | Bengals | 3 | 9:22 | 3 | 13 | CIN 24 | 17-6 | Jimmy Garoppolo pass complete short middle to George Kittle for 16 yards (tackle by Ricardo Allen) | 16 | | | |
2021-11-07 | 49ers | Cardinals | 2 | 0:42 | 3 | 11 | CRD 24 | 0-17 | Jimmy Garoppolo pass complete deep left to Brandon Aiyuk for 16 yards (tackle by Marco Wilson and Byron Murphy) | 16 | | | |
2021-09-12 | 49ers | Lions | 4 | 12:47 | 3 | 10 | SFO 47 | 38-17 | Jimmy Garoppolo pass complete short right to Jamycal Hasty for 15 yards (tackle by Jeff Okudah and Will Harris) | 15 | | | |
2021-09-19 | 49ers | Eagles | 4 | 15:00 | 3 | 7 | SFO 41 | 7-3 | Jimmy Garoppolo pass complete short middle to Deebo Samuel for 15 yards (tackle by Genard Avery and Anthony Harris) | 15 | | | |
2021-10-10 | 49ers | Cardinals | 4 | 12:39 | 3 | 7 | SFO 23 | 7-10 | Trey Lance scrambles up the middle for 15 yards (tackle by Antonio Hamilton). Penalty on Antonio Hamilton: Illegal Contact, 5 yards (accepted) | 15 | | | |
2021-10-10 | 49ers | Cardinals | 4 | 10:07 | 3 | 14 | SFO 39 | 7-10 | Trey Lance pass complete short middle to Ross Dwelley for 13 yards (tackle by Jalen Thompson and Budda Baker) | 13 | | | |
2021-11-21 | 49ers | Jaguars | 1 | 7:25 | 3 | 12 | JAX 47 | 0-0 | Jimmy Garoppolo pass complete short right to Brandon Aiyuk for 13 yards (tackle by Myles Jack) | 13 | | | |
2021-09-26 | 49ers | Packers | 4 | 1:53 | 3 | 10 | GNB 36 | 21-27 | Jimmy Garoppolo pass complete short right to Deebo Samuel for 12 yards (tackle by Jaire Alexander) | 12 | | | |
2021-12-12 | 49ers | Bengals | 1 | 7:19 | 3 | 14 | CIN 27 | 0-0 | Jimmy Garoppolo pass complete short left to Jauan Jennings for 12 yards. Jauan Jennings fumbles (forced by Vonn Bell) (tackle by Chidobe Awuzie), recovered by Jauan Jennings at CIN-15 (tackle by Chidobe Awuzie) (tackle by Vonn Bell) (tackle by Vonn Bell) | 12 | | | |
2021-10-10 | 49ers | Cardinals | 3 | 9:58 | 3 | 17 | SFO 48 | 0-10 | Trey Lance pass complete short middle to Ross Dwelley for 12 yards (tackle by Budda Baker) | 12 | | | |
2021-09-12 | 49ers | Lions | 4 | 10:45 | 3 | 18 | DET 46 | 38-17 | Jimmy Garoppolo pass complete short left to George Kittle for 12 yards (tackle by Kevin Strong) | 12 | | | |
2022-01-02 | 49ers | Texans | 2 | 11:41 | 3 | 19 | SFO 48 | 0-0 | Trey Lance pass complete short middle to Jauan Jennings for 12 yards (tackle by Christian Kirksey) | 12 | | | |
2021-12-23 | 49ers | Titans | 4 | 10:13 | 3 | 21 | SFO 45 | 10-17 | Jimmy Garoppolo pass complete short middle to Deebo Samuel for 12 yards (tackle by Jayon Brown and Jackrabbit Jenkins) | 12 | | | |
2021-12-23 | 49ers | Titans | 3 | 5:37 | 3 | 7 | SFO 28 | 10-10 | Jimmy Garoppolo pass complete short right to Jauan Jennings for 11 yards (tackle by Buster Skrine and Amani Hooker) | 11 | | | |
2021-11-15 | 49ers | Rams | 3 | 2:28 | 3 | 7 | SFO 30 | 24-7 | Jimmy Garoppolo pass complete short middle to Deebo Samuel for 11 yards (tackle by David Long) | 11 | | | |
2021-11-28 | 49ers | Vikings | 3 | 0:56 | 3 | 15 | MIN 15 | 31-26 | Jimmy Garoppolo pass complete short middle to Kyle Juszczyk for 11 yards (tackle by Nick Vigil and Josh Metellus) | 11 | | | |
2021-09-12 | 49ers | Lions | 4 | 0:58 | 3 | 13 | DET 46 | 41-33 | Jimmy Garoppolo pass complete short middle to Deebo Samuel for 11 yards. Deebo Samuel fumbles (forced by Trey Flowers), recovered by Ifeatu Melifonwu at DET-30 (tackle by Trey Flowers) | 11 | | | |
2021-11-07 | 49ers | Cardinals | 3 | 5:03 | 3 | 11 | CRD 11 | 13-31 | Jimmy Garoppolo pass complete short middle to Brandon Aiyuk for 11 yards, touchdown | 11 | | | |
2021-10-03 | 49ers | Seahawks | 2 | 10:55 | 3 | 10 | SFO 14 | 7-0 | Jimmy Garoppolo pass complete short right to Deebo Samuel for 10 yards (tackle by Sidney Jones) | 10 | | | |
2021-09-19 | 49ers | Eagles | 1 | 14:21 | 3 | 14 | SFO 21 | 0-0 | Jimmy Garoppolo pass complete short middle to Deebo Samuel for 10 yards (tackle by Eric Wilson and Anthony Harris) | 10 | | | |
2021-10-24 | 49ers | Colts | 2 | 3:11 | 3 | 13 | SFO 18 | 12-7 | Jimmy Garoppolo pass complete short middle to Deebo Samuel for 10 yards. Deebo Samuel fumbles (forced by Shaquille Leonard), recovered by Anthony Chesley at SF-28 (tackle by George Odum and Shaquille Leonard) | 10 | | | |
2021-12-05 | 49ers | Seahawks | 2 | 3:11 | 3 | 8 | SFO 39 | 17-14 | Jimmy Garoppolo pass complete short right to Trent Sherfield for 9 yards (tackle by Sidney Jones and Bobby Wagner) | 9 | | | |
2021-11-15 | 49ers | Rams | 4 | 1:17 | 3 | 14 | RAM 37 | 31-10 | Elijah Mitchell left end for 8 yards (tackle by Taylor Rapp) | 8 | | | |
2021-11-15 | 49ers | Rams | 1 | 2:01 | 3 | 6 | RAM 8 | 6-0 | Jimmy Garoppolo pass complete short right to George Kittle for 8 yards, touchdown | 8 | | | |
2021-09-26 | 49ers | Packers | 3 | 7:45 | 3 | 8 | GNB 8 | 13-17 | Jimmy Garoppolo pass complete short right to Brandon Aiyuk for 8 yards, touchdown | 8 | | | |
2021-09-19 | 49ers | Eagles | 1 | 4:00 | 3 | 9 | SFO 26 | 0-3 | Jimmy Garoppolo pass complete to Jamycal Hasty for 8 yards (tackle by Fletcher Cox) | 8 | | | |
2022-01-09 | 49ers | Rams | 2 | 5:19 | 3 | 6 | SFO 29 | 0-17 | Jimmy Garoppolo pass complete short left to Jauan Jennings for 8 yards (tackle by Taylor Rapp) | 8 | | | |
2021-10-03 | 49ers | Seahawks | 2 | 0:59 | 3 | 10 | SFO 38 | 7-7 | Jimmy Garoppolo pass complete short right to Kyle Juszczyk for 8 yards (tackle by Bobby Wagner and Sidney Jones) | 8 | | | |
2021-12-12 | 49ers | Bengals | 4 | 2:55 | 3 | 10 | SFO 29 | 20-13 | Jimmy Garoppolo pass complete short left to George Kittle for 8 yards (tackle by Tre Flowers) | 8 | | | |
2021-11-07 | 49ers | Cardinals | 4 | 0:50 | 3 | 7 | SFO 27 | 17-31 | Jimmy Garoppolo pass complete short right to Deebo Samuel for 7 yards (tackle by Robert Alford and Budda Baker) | 7 | | | |
2021-12-05 | 49ers | Seahawks | 2 | 10:24 | 3 | 21 | SEA 39 | 14-7 | Jimmy Garoppolo pass complete to Trent Sherfield for 7 yards (tackle by Ryan Neal) | 7 | | | |
2021-09-12 | 49ers | Lions | 1 | 6:29 | 3 | 6 | DET 12 | 0-0 | Jimmy Garoppolo pass complete short left to Mohamed Sanu for 7 yards (tackle by Jeff Okudah) | 7 | | | |
2021-10-03 | 49ers | Seahawks | 4 | 2:45 | 3 | 8 | SEA 30 | 13-28 | Trey Lance pass complete short left to Mohamed Sanu for 7 yards (tackle by D.J. Reed) | 7 | | | |
2021-10-03 | 49ers | Seahawks | 4 | 6:57 | 3 | 9 | SFO 41 | 13-28 | Trey Lance scrambles up the middle for 7 yards (tackle by Marquise Blair) | 7 | | | |
2021-10-03 | 49ers | Seahawks | 2 | 14:17 | 3 | 15 | SEA 30 | 7-0 | Jimmy Garoppolo pass complete short left to George Kittle for 7 yards (tackle by Ryan Neal) | 7 | | | |
2021-11-21 | 49ers | Jaguars | 2 | 8:31 | 3 | 6 | JAX 6 | 16-0 | Jimmy Garoppolo pass complete short middle to Brandon Aiyuk for 6 yards, touchdown | 6 | | | |
2022-01-02 | 49ers | Texans | 2 | 1:34 | 3 | 9 | SFO 27 | 0-7 | Trey Lance pass complete short left to Kyle Juszczyk for 6 yards (tackle by Eric Murray) | 6 | | | |
2021-12-19 | 49ers | Falcons | 1 | 11:45 | 3 | 7 | SFO 4 | 0-0 | Jimmy Garoppolo pass complete short left to Kyle Juszczyk for 6 yards (tackle by Duron Harmon and Deion Jones) | 6 | | | |
2021-10-03 | 49ers | Seahawks | 4 | 8:52 | 3 | 7 | SFO 23 | 13-28 | Trey Lance scrambles up the middle for 6 yards (tackle by Ryan Neal) | 6 | | | |
2022-01-02 | 49ers | Texans | 1 | 11:34 | 3 | 10 | SFO 22 | 0-0 | Trey Lance scrambles left end for 6 yards (tackle by DeMarcus Walker) | 6 | | | |
2021-12-23 | 49ers | Titans | 2 | 9:16 | 3 | 26 | OTI 36 | 7-0 | Jimmy Garoppolo pass complete short left to Deebo Samuel for 6 yards (tackle by Dane Cruikshank and Bud Dupree) | 6 | | | |
2022-01-02 | 49ers | Texans | 3 | 2:18 | 3 | 7 | SFO 41 | 10-7 | Trey Lance scrambles right end for 6 yards (tackle by Kamu Grugier-Hill) | 6 | | | |
2021-10-31 | 49ers | Bears | 1 | 3:12 | 3 | 9 | CHI 36 | 0-3 | Jimmy Garoppolo pass complete short right to Jamycal Hasty for 6 yards (tackle by Roquan Smith) | 6 | | | |
2021-10-10 | 49ers | Cardinals | 1 | 5:35 | 3 | 7 | CRD 39 | 0-7 | Trey Lance up the middle for 5 yards (tackle by Zach Allen) | 5 | | | |
2021-11-21 | 49ers | Jaguars | 4 | 6:20 | 3 | 7 | JAX 30 | 27-3 | Jimmy Garoppolo scrambles left end for 3 yards (tackle by Nevin Lawson) | 3 | | | |
2021-12-19 | 49ers | Falcons | 1 | 2:06 | 3 | 8 | ATL 15 | 0-3 | Jimmy Garoppolo pass complete short right to Jamycal Hasty for 3 yards (tackle by Jaylinn Hawkins) | 3 | | | |
2021-09-12 | 49ers | Lions | 3 | 12:04 | 3 | 20 | DET 36 | 31-10 | Trey Lance up the middle for 2 yards (tackle by Will Harris) | 2 | | | |
2022-01-09 | 49ers | Rams | 5 | 2:58 | 3 | 7 | RAM 7 | 24-24 | Jimmy Garoppolo pass complete short left to George Kittle for 1 yard (tackle by Terrell Burgess) | 1 | | | |
2021-10-24 | 49ers | Colts | 3 | 2:04 | 3 | 19 | SFO 16 | 12-20 | Jimmy Garoppolo pass complete short left to Jamycal Hasty for 1 yard (tackle by Kenny Moore and Andrew Sendejo) | 1 | | | |
2021-09-19 | 49ers | Eagles | 2 | 8:05 | 3 | 8 | PHI 39 | 0-3 | Deebo Samuel right end for 1 yard (tackle by Eric Wilson and Javon Hargrave) | 1 | | | |
2021-10-31 | 49ers | Bears | 4 | 2:29 | 3 | 12 | CHI 15 | 30-22 | Jamycal Hasty right end for 1 yard (tackle by Tashaun Gipson) | 1 | | | |
2021-12-19 | 49ers | Falcons | 4 | 1:15 | 3 | 6 | SFO 44 | 31-13 | Jimmy Garoppolo pass complete short right to Deebo Samuel for 1 yard (tackle by Adetokunbo Ogundeji and Grady Jarrett) | 1 | | | |
2021-11-15 | 49ers | Rams | 4 | 5:12 | 3 | 10 | SFO 11 | 31-7 | Elijah Mitchell left guard for 1 yard (tackle by Troy Reeder and Greg Gaines) | 1 | | | |
2021-12-19 | 49ers | Falcons | 4 | 9:51 | 3 | 9 | SFO 10 | 31-13 | Jimmy Garoppolo pass incomplete intended for Deebo Samuel (defended by AJ Terrell) | 0 | | | |
2021-11-15 | 49ers | Rams | 3 | 1:03 | 3 | 6 | SFO 45 | 24-7 | Jimmy Garoppolo pass incomplete deep left intended for George Kittle | 0 | | | |
2022-01-02 | 49ers | Texans | 4 | 3:25 | 3 | 9 | HTX 9 | 17-7 | Trey Lance pass incomplete short right intended for Deebo Samuel | 0 | | | |
2021-11-21 | 49ers | Jaguars | 1 | 9:11 | 3 | 6 | SFO 50 | 0-0 | Jimmy Garoppolo sacked by Dawuane Smoot for no gain. Penalty on Rayshawn Jenkins: Defensive Holding, 5 yards (accepted) (no play) | 0 | | | |
2021-10-10 | 49ers | Cardinals | 3 | 6:38 | 3 | 22 | CRD 46 | 0-10 | Trey Lance pass incomplete deep left intended for Kyle Juszczyk | 0 | | | |
2021-12-23 | 49ers | Titans | 2 | 9:41 | 3 | 11 | OTI 21 | 7-0 | Jimmy Garoppolo scrambles right end for no gain (tackle by Kevin Byard). Penalty on Bud Dupree: Defensive Offside, 5 yards (declined) . Penalty on Trent Williams: Face Mask (15 Yards), 15 yards (accepted) (no play) | 0 | | | |
2021-10-31 | 49ers | Bears | 2 | 9:42 | 3 | 7 | CHI 34 | 3-10 | Jimmy Garoppolo pass incomplete short middle intended for Mohamed Sanu (defended by DeAndre Houston-Carson) | 0 | | | |
2021-11-07 | 49ers | Cardinals | 4 | 13:12 | 3 | 13 | CRD 39 | 14-31 | Jimmy Garoppolo pass incomplete short right intended for George Kittle | 0 | | | |
2021-12-05 | 49ers | Seahawks | 4 | 11:13 | 3 | 8 | SFO 23 | 23-30 | Jimmy Garoppolo pass complete to Brandon Aiyuk for 22 yards (tackle by D.J. Reed) SEA challenged the pass completion ruling, and the original play was overturned. Jimmy Garoppolo pass incomplete deep left intended for Brandon Aiyuk (defended by D.J. Reed) | 0 | | | |
2022-01-09 | 49ers | Rams | 1 | 2:08 | 3 | 8 | SFO 28 | 0-3 | Jimmy Garoppolo pass incomplete deep right intended for Jamycal Hasty (defended by Travin Howard) | 0 | | | |
2021-10-10 | 49ers | Cardinals | 3 | 10:26 | 3 | 7 | CRD 42 | 0-10 | Trey Lance up the middle for no gain (tackle by Markus Golden). Penalty on Mike McGlinchey: Offensive Holding, 10 yards (accepted) (no play) | 0 | | | |
2021-09-19 | 49ers | Eagles | 1 | 9:43 | 3 | 11 | SFO 19 | 0-0 | Jimmy Garoppolo pass incomplete short left intended for Mohamed Sanu | 0 | | | |
2021-09-12 | 49ers | Lions | 2 | 0:12 | 3 | 7 | DET 22 | 28-10 | Jimmy Garoppolo pass incomplete short left | 0 | | | |
2021-10-31 | 49ers | Bears | 1 | 11:13 | 3 | 14 | CHI 39 | 0-0 | Jimmy Garoppolo scrambles up the middle for no gain (tackle by Alec Ogletree). Penalty on Trent Williams: Offensive Holding, 10 yards (accepted) (no play) | 0 | | | |
2021-10-10 | 49ers | Cardinals | 2 | 4:01 | 3 | 11 | SFO 24 | 0-10 | Trey Lance pass incomplete deep middle intended for Mohamed Sanu | 0 | | | |
2021-10-03 | 49ers | Seahawks | 2 | 5:05 | 3 | 6 | SFO 46 | 7-0 | Jimmy Garoppolo pass incomplete short left intended for George Kittle (defended by Ryan Neal) | 0 | | | |
2021-12-12 | 49ers | Bengals | 4 | 0:04 | 3 | 10 | CIN 29 | 20-20 | Robbie Gould 47 yard field goal no good | 0 | | | |
2021-12-12 | 49ers | Bengals | 3 | 7:56 | 3 | 6 | CIN 6 | 17-6 | Jimmy Garoppolo pass incomplete short middle intended for Kyle Juszczyk (defended by Germaine Pratt) | 0 | | | |
2021-11-15 | 49ers | Rams | 4 | 12:02 | 3 | 6 | RAM 40 | 24-7 | Jeff Wilson up the middle for no gain (tackle by Aaron Donald and Jordan Fuller) | 0 | | | |
2021-11-28 | 49ers | Vikings | 3 | 5:09 | 3 | 9 | MIN 28 | 28-20 | Jimmy Garoppolo pass incomplete deep right intended for Deebo Samuel | 0 | | | |
2021-12-12 | 49ers | Bengals | 2 | 0:30 | 3 | 7 | CIN 28 | 10-6 | Jimmy Garoppolo pass incomplete short left | 0 | | | |
2021-11-07 | 49ers | Cardinals | 1 | 4:51 | 3 | 16 | SFO 36 | 0-7 | Jimmy Garoppolo pass incomplete short right intended for Deebo Samuel | 0 | | | |
2021-10-03 | 49ers | Seahawks | 4 | 1:50 | 3 | 10 | SEA 21 | 13-28 | Trey Lance pass incomplete short left intended for Deebo Samuel | 0 | | | |
2021-09-19 | 49ers | Eagles | 3 | 10:06 | 3 | 6 | PHI 49 | 7-3 | Jimmy Garoppolo pass incomplete short left intended for Deebo Samuel (defended by Steven Nelson) | 0 | | | |
2021-12-19 | 49ers | Falcons | 2 | 2:00 | 3 | 7 | ATL 42 | 10-10 | Jimmy Garoppolo pass incomplete short left intended for Brandon Aiyuk. Penalty on Fabian Moreau: Defensive Pass Interference, 14 yards (accepted) (no play) | 0 | | | |
2022-01-09 | 49ers | Rams | 3 | 0:05 | 3 | 7 | SFO 35 | 17-17 | Jimmy Garoppolo pass incomplete short left intended for Jauan Jennings | 0 | | | |
2021-12-12 | 49ers | Bengals | 2 | 1:16 | 3 | 15 | SFO 21 | 10-6 | Jimmy Garoppolo pass incomplete deep left intended for Travis Benjamin (defended by Chidobe Awuzie) | 0 | | | |
2021-10-24 | 49ers | Colts | 2 | 6:54 | 3 | 8 | SFO 22 | 12-7 | Jimmy Garoppolo pass incomplete short left intended for Ross Dwelley | 0 | | | |
2021-11-07 | 49ers | Cardinals | 3 | 12:10 | 3 | 19 | SFO 16 | 7-24 | Jimmy Garoppolo pass incomplete deep middle intended for Mohamed Sanu | 0 | | | |
2021-09-26 | 49ers | Packers | 4 | 11:54 | 3 | 14 | SFO 15 | 14-24 | Jimmy Garoppolo pass incomplete deep middle intended for Brandon Aiyuk. Penalty on Eric Stokes: Defensive Pass Interference, 35 yards (accepted) (no play) | 0 | | | |
2021-10-24 | 49ers | Colts | 1 | 8:20 | 3 | 10 | CLT 16 | 6-0 | Jimmy Garoppolo pass incomplete deep right intended for Jamycal Hasty | 0 | | | |
2021-09-26 | 49ers | Packers | 1 | 7:44 | 3 | 6 | SFO 41 | 0-3 | Jimmy Garoppolo pass incomplete short middle intended for Mohamed Sanu (defended by Chandon Sullivan) | 0 | | | |
2021-11-15 | 49ers | Rams | 3 | 4:50 | 3 | 14 | RAM 32 | 21-7 | Jimmy Garoppolo pass incomplete short left intended for George Kittle | 0 | | | |
2021-11-07 | 49ers | Cardinals | 4 | 8:36 | 3 | 8 | CRD 8 | 14-31 | Jimmy Garoppolo pass incomplete short middle | 0 | | | |
2021-11-28 | 49ers | Vikings | 2 | 3:47 | 3 | 8 | MIN 44 | 7-14 | Jauan Jennings pass complete short left to Jeff Wilson for no gain (tackle by Sheldon Richardson). Penalty on Patrick Peterson: Defensive Holding, 5 yards (accepted) (no play) | 0 | | | |
2021-11-28 | 49ers | Vikings | 1 | 12:09 | 3 | 12 | MIN 48 | 0-0 | Jimmy Garoppolo pass intended for Deebo Samuel is intercepted by Harrison Smith at MIN-41 and returned for 10 yards (tackle by Tom Compton) | 0 | | | |
2021-12-05 | 49ers | Seahawks | 1 | 11:44 | 3 | 10 | SFO 15 | 0-7 | Jimmy Garoppolo pass incomplete short middle intended for George Kittle | 0 | | | |
2022-01-09 | 49ers | Rams | 2 | 9:03 | 3 | 27 | SFO 8 | 0-10 | Elijah Mitchell up the middle for -1 yards (tackle by Aaron Donald and Greg Gaines) | -1 | | | |
2021-09-19 | 49ers | Eagles | 4 | 0:39 | 3 | 12 | SFO 24 | 17-11 | Jimmy Garoppolo kneels for -1 yards | -1 | | | |
2021-10-24 | 49ers | Colts | 2 | 0:01 | 3 | 13 | SFO 30 | 12-13 | Jimmy Garoppolo kneels for -1 yards | -1 | | | |
2021-10-31 | 49ers | Bears | 4 | 0:31 | 3 | 12 | SFO 48 | 33-22 | Jimmy Garoppolo kneels for -1 yards | -1 | | | |
2021-10-03 | 49ers | Seahawks | 4 | 11:19 | 3 | 7 | SFO 18 | 13-28 | Trey Lance sacked by Darrell Taylor for -1 yards | -1 | | | |
2021-11-15 | 49ers | Rams | 3 | 13:07 | 3 | 8 | SFO 42 | 21-7 | Jimmy Garoppolo sacked by Taylor Rapp for -3 yards | -3 | | | |
2021-11-07 | 49ers | Cardinals | 1 | 13:28 | 3 | 10 | CRD 42 | 0-0 | Jimmy Garoppolo sacked by Markus Golden for -4 yards | -4 | | | |
2021-12-05 | 49ers | Seahawks | 3 | 10:33 | 3 | 8 | SFO 5 | 23-23 | Jimmy Garoppolo sacked by Carlos Dunlap for -5 yards, safety. | -5 | | | |
2021-11-28 | 49ers | Vikings | 3 | 2:17 | 3 | 9 | SFO 38 | 31-26 | Jimmy Garoppolo sacked by Armon Watts for -5 yards | -5 | | | |
2021-12-23 | 49ers | Titans | 2 | 3:57 | 3 | 10 | SFO 22 | 10-0 | Jimmy Garoppolo sacked by Denico Autry for -7 yards | -7 | | | |
2021-12-12 | 49ers | Bengals | 4 | 12:51 | 3 | 11 | SFO 46 | 20-6 | Jimmy Garoppolo sacked by Larry Ogunjobi for -9 yards | -9 | | | |
2022-01-09 | 49ers | Rams | 4 | 2:02 | 3 | 9 | SFO 26 | 17-24 | Jimmy Garoppolo sacked by Von Miller for -9 yards | -9 | | | |
2021-12-12 | 49ers | Bengals | 4 | 7:31 | 3 | 9 | SFO 40 | 20-13 | Jimmy Garoppolo sacked by B.J. Hill for -9 yards | -9 | | | |
2021-12-12 | 49ers | Bengals | 1 | 13:34 | 3 | 11 | SFO 24 | 0-0 | Jimmy Garoppolo sacked by Trey Hendrickson for -10 yards | -10 | | | |
2021-11-28 | 49ers | Vikings | 1 | 1:15 | 3 | 6 | SFO 45 | 7-7 | Jimmy Garoppolo sacked by D.J. Wonnum for -10 yards | -10 | | | |
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